An experimental study conducted by researchers from the Andrés Bello University, Talca University, Finis Terrae University, and the Autonomous University of Chile showed that resistance training may help limit muscle mass loss and maintain its strength and function in cases of chronic cholestatic liver disease, which affects bile flow from the liver.
The study, published in the scientific journal "Scientific Reports" yesterday Tuesday, noted that researchers evaluated the effect of resistance training in limiting muscle atrophy associated with the disease. The study relied on experiments conducted on male mice, in which the disease was induced using a special diet over a period of six weeks. Researchers then evaluated the effect of training on muscle mass, strength, and function, along with associated cellular changes.
The results showed that resistance training helped maintain the structure of muscle fibers and mitochondrial function, which are cellular components responsible for energy production. It also contributed to regulating biological processes related to muscle protein synthesis and limiting their breakdown. Muscle atrophy is a complication that may accompany chronic liver diseases, leading to a decline in muscle mass and strength, which may affect the ability to perform daily activities and quality of life.
Researchers emphasized that the results are still in the experimental stage and cannot be directly generalized to humans before additional clinical studies are conducted to verify the effectiveness and safety of resistance training in patients with these diseases. The study highlights the importance of continuing research on the relationship between liver health and muscle function, and exploring supportive measures that may help limit complications associated with chronic diseases.
Source: Syrian Arab News Agency (SANA)
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